March 1995
Supplement
Volume 125, Number 3S

Official Publication of the American Institute of Nutrition
First International symposium on the Role of Soy in Preventing and Treating Chronic Disease
Proceedings from a symposium held in Mesa, Arizona, on February 20-23, 1994
Guest Editors:
Mark Messina and John w. Erdman, Jr.
These proceedings are sponsored by Protein Technologies International, the soybean
growers
from Nebraska, Indiana and Iowa and the United Soybean Board.
Table of Contents
- Modern Applications for an Ancient Bean: Soybeans and the Prevention and Treatment of
Chronic Disease. Mark Messina
Soy Intake and Cholesterol Reduction
- Dietary Protein, Cholesterol and Atherosclerosis: A Review of the Early History. David
Kritchevsky
- Soy Consumption and Cholesterol Reduction: Review of Animal and Human Studies.
Kenneth K. Carroll and Elzbieta M. Kurowska
- Soy and Cholesterol Reduction: Clinical Experience. Cesare R. Sirtori, Maria R. Lovati,
Cristina Manzoni, Marco Monetti, Franco Pazzucconi and Ennio Gatti
Soy and Cholesterol Reduction: Hypothesized Mechanisms
- Overview of Proposed Mechanisms for the Hypocholesterolemic Effects of Soy. Susan M.
Potter
- Cholesterol Synthesis and Absorption by 2H20 and 180-Cholesterol and
Hypocholesterolemic Effect of Soy Protein. William W. Wong, David L. Hachey, Lucinda L. Clarke and Shide Zhang
- Soy Protein, Thyroid Regulation and Cholesterol Metabolism. William A. Forsythe III
Soy and Heart Disease Prevention: Potential Mechanisms Unrelated to Cholesterol
Reduction
- Biology of Atherosclerotic Plaque Formation: Possible Role of Growth Factors in Lesion
Development and the Potential Impact of Soy. Elaine W. Raines and Russell Ross
- Thrombotic Mechanisms in Atherosclerosis: Potential Impact of Soy Proteins. Josiah N.
Wilcox and Barbara F. Blumenthal
- Protective Effects of Soy Protein on the Peroxidizability of Lipoproteins in Cerebrovascular
Diseases. Takemichi Kanazawa, Tomohiro Osanai, Xiao Shu Zhang, Tsugumichi Uemura,
Xue Ze Yin Kogo Onodera, Yasaburo Oike and Kazuyoshi Ohkubo
Potential Public Health Impact of Soy Protein
- Overview: Dietary Approaches for Reducing Cardiovascular Disease Risks. Johanna Dwyer
- Incorporating Soy Proteins into Baked Products for Use in Clinical Studies. Barbara P.
Klein, Aiko K. Perry
and Nancy Adair
- Perspectives on Soy Protein as a Nonpharmacological Approach for Lowering Cholesterol.
Anne Carol
Goldberg
- Diet and Heart Disease: Health Claims. Elizabeth A. Yetley and Youngmee K. Park
Soy Intake and Cancer Risk: Animal and Epidemiologic Studies
- Soy and Experimental Cancer: Animal Studies. E. J. Hawrylewicz, Jose J. Zapata and William H. Blair
- Epidemiology of Soy and Cancer: Perspectives and Directions. Victoria Persky and Linda Van Horn
Nonisopavone Soybean Anticarcinogens
- Cancer Chemoprevention Agent Development Strategies for Genistein. Vernon E. Steele, Michael A
Pereira Caroline C. Sigman and Gary 1. Kelloff
- Saponins as Anticarcinogens. A. V. Rao and M-K Sung
- Inositol Phosphates Have Novel Anti-Cancer Function. Abulkalam M. Shamsuddin
- The Evidence for Soybean Products as Cancer Preventive Agents. Ann R. Kennedy
- Possible Adverse Effects of Soybean Anticarcinogens. Irvin E. Liener
Soybean IsoflaDones and Cancer Risk
- In Vitro Hormonal Effects of Soybean Isoflavones. Agostino Molteni, Loredana Brizio-Molteni and
Victoria Persky
- Soybean Phytoestrogen Intake and Cancer Risk. C. Herman T. Adlercreutz, Barry R. Goldin, Sherwood L.
Gorbach, Krister A. V. Hockerstedt, Shaw Watanabe, Esa K. Hamalainen, M. Helene Markkanen, Taru
H. Makela, Kristiina T. Wahala, Tapio A. Hase and Theodore Fotsis
Anticancer Effects of Genistein
- Effects of Genistein on In Vitro and In Vivo Models of Cancer. Stephen Barnes
- Evaluation of the Biochemical Targets of Genistein in Tumor Cells. Greg Peterson
- Genistein, a Dietary Ingested Isoflavonoid, Inhibits Cell Proliferation and InVitro Angiogenesis. Theodore
Fotsis, Michael Pepper, Herman Adlercreutz, Tapio Hase, Roberto Montesano and Lothar Schweigerer
This supplement to The Journal of Nutrition includes papers and abstracts presented at the
First International
Symposium on the Role of Soy in Preventing and Treating Chronic Disease, held in Mesa,
Arizona, February
20-23, 1994. This supplement is the responsibility of the guest editors, to whom the Editor
of The Journal of
Nutrition has delegated supervision of both technical conformity to the published
regulations of The Journal of
Nutrition and general oversight of the scientific merit of each article. Each article in this
section was subject to strict peer review before publication, as are all articles published in The
Journal of Nutrition.
The symposium was sponsored by Protein Technologies International, the soybean
growers from Nebraska
Indiana and Iowa and the United Soybean Board. The opinions expressed in this
publication are those of the authors and are not attributable to the sponsors or the publisher,
editor, or editorial board
of The Journal of Nutrition. The costs of publication of this supplement were defrayed in part by
the payment of page charges.
This publication must therefore be hereby marked "advertisement" in accordance with 18
U.S.C. Section 1734
solely to indicate this fact.